Trazodone Impurity 109 CAS CATO-C4X-1772109
| CAS No. | CATO-C4X-1772109 |
| Molecular Formula | C19H33ClN3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trazodone Impurity 109 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Trazodone Impurity 109 (CAS CATO-C4X-1772109), a pharmacopoeial impurity reference standard (molecular formula C19H33ClN3C2HF3O2, MW 452.97 g/mol) used for the identification and quantification of trace impurities in APIs.
Trazodone Impurity 109 (C19H33ClN3C2HF3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Trazodone Impurity 109 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H33ClN3 2*C2HF3O2 |
| Molecular Weight | 452.97 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone Impurity 4 (CAS 1263278-79-0)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
Recommended Standards
- Cipepofol Impurity 2 (CAS 1637741-46-8)
- Iomeprol Impurity 12 (CAS CATO-C4X-182012)
- Atropine Impurity 38 (CAS 5226-98-2)
- 5-Chloro-1-(4-fluorophenyl)-1H-pyrazole-4-carbonitrile (CAS 1050619-83-4)
- Methyl 2-[2-formyl-4-(2-pyrimidinyl)phenoxy]acetate (CAS 351365-86-1)
- Derquantel (CAS 187865-22-1)
- 1,4-Bis(4,5-dihydrooxazol-2-yl)benzene (CAS 7426-75-7)
- 6-(chloromethyl)-3-phenyl-5,6-dihydro-4H-1,2,4-oxadiazine (CAS 56493-89-1)
- Urapidil Impurity 34 (CAS 62845-30-1)
- Semaglutide (CAS 910463-68-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com