Nintedanib Impurity 56 CAS CATO-C4X-181456
| CAS No. | CATO-C4X-181456 |
| Molecular Formula | C20H16ClNO5 |
| Molecular Weight | 385.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Nintedanib Impurity 56 (CAS CATO-C4X-181456) is a certified pharmaceutical impurity reference standard with the molecular formula C20H16ClNO5 and a molecular weight of 385.80 g/mol.
Based on its molecular formula C20H16ClNO5, Nintedanib Impurity 56 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 385.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H16ClNO5 |
| Molecular Weight | 385.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Nintedanib Standards
- Nintedanib Impurity 57 (CAS 1174335-83-1)
- Nintedanib Impurity 58 (CAS 1160293-24-2)
- Nintedanib Impurity 116 (CAS CATO-C4X-1814116)
- Nintedanib impurity 82 (CAS 2101947-36-6)
- Nintedanib Impurity 133 (CAS CATO-C4X-1814133)
- Nintedanib Impurity N4 (CAS 1987887-92-2)
- Nintedanib Impurity 28 (CAS CATO-C4X-181428)
- Nintedanib Impurity 188 (CAS 2676997-47-8)
Recommended Standards
- Lenvatinib Impurity 173 (CAS CATO-C4X-1140173)
- Ethyl 4-{[(4-chlorophenyl)methyl]amino}-6-nitroquinoline-3-carboxylate (CAS 478248-26-9)
- 6-Chloro-2-morpholino-N-(4-nitrophenyl)quinazolin-4-amine (CAS 75426-57-2)
- (2Z)-2-(Benzenesulfonyl)-1-(2-chloro-4,5-difluorophenyl)-3-(dimethylamino)prop-2-en-1-one (CAS 400088-09-7)
- Itraconazole Impurity 19 (CAS CATO-C4X-149719)
- Desmopressin EP Impurity C (CAS CATO-C4X-221525)
- Telmisartan Impurity N5 (CAS 567-15-7)
- 3,3-Dimethylazetidine (CAS 19816-92-3)
- 3-(aminomethyl)pentan-1-ol (CAS 231282-15-8)
- HISTIDINE impurity 3 (CAS CATO-C4X-32393)
- [1-(1-aminoethyl)cyclopropyl]methanol hydrochloride (CAS 1955553-73-7)
- (3R,4S,5R)-4-Amino-5-phenylpyrrolidine-3-carboxylic acid (CAS 474759-40-5)
- (±)-Mevalonolactone-4,4,5,5-d4 (CAS 349553-98-6)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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