Nebivolol Impurity 23 CAS CATO-C4X-196823
| CAS No. | CATO-C4X-196823 |
| Molecular Formula | C11H10ClFO2 |
| Molecular Weight | 228.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Nebivolol Impurity 23 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Nebivolol Impurity 23 (CAS CATO-C4X-196823), a pharmacopoeial impurity reference standard (molecular formula C11H10ClFO2, MW 228.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10ClFO2 |
| Molecular Weight | 228.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Nebivolol Standards
- Nebivolol Impurity 24 (CAS CATO-C4X-196824)
- Nebivolol Impurity 27 (CAS CATO-C4X-196827)
- Nebivolol Impurity 68 (CAS CATO-C4X-196868)
- Nebivolol Impurity 71 (CAS CATO-C4X-196871)
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Nebivolol Impurity 72 (CAS CATO-C4X-196872)
- Nebivolol Impurity 73 (CAS CATO-C4X-196873)
- Nebivolol Impurity 10 (CAS CATO-C4X-196810)
Recommended Standards
- Phosphorochloridic acid, dibutyl ester (CAS 819-43-2)
- Methyl (2Z)-2-(chloromethyl)-3-(4-fluorophenyl)prop-2-enoate (CAS 847653-89-8)
- Ethyl (E)-3-(4-chloro-2-fluorophenyl)acrylate (CAS 500102-63-6)
- di-tert-butylChlorophosphate (CAS 56119-60-9)
- Rtitrexed Impurity 21 (CAS CATO-C4X-138621)
- Progesterone Impurity 79 (CAS CATO-C4X-150279)
- Propofol Impurity 31 (CAS 2918851-48-4)
- rac-Sitagliptin Phosphate (CAS 823817-57-8)
- N-(Boc-PEG2)-N-bis(PEG3-azide) (CAS 2353409-46-6)
- 3-(((4-Bromophenyl)thio)methyl)piperidine (CAS 1249972-00-6)
- [1-(2-Methoxyethyl)-1H-imidazol-5-yl]methanamine hydrochloride (CAS 1707369-72-9)
- (R)-3-(((benzyloxy)carbonyl)amino)-2-phenylpropanoic acid (CAS 1040-59-1)
- N-(3,4-Dichlorophenyl)-5-oxoprolinamide (CAS 4108-15-0)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com