Crisaborole impurity 132 CAS CATO-C4X-2021132
| CAS No. | CATO-C4X-2021132 |
| Molecular Formula | C15H10BrNO2 |
| Molecular Weight | 316.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C15H10BrNO2, Crisaborole impurity 132 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Crisaborole impurity 132 (CAS CATO-C4X-2021132, C15H10BrNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Crisaborole impurity 132 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H10BrNO2 |
| Molecular Weight | 316.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Crisaborole Standards
- Crisaborole lmpurity 73 (CAS 2473730-47-9)
- Crisaborole lmpurity 95 (CAS CATO-C4X-202195)
- Crisaborole impurity 118 (CAS CATO-C4X-2021118)
- Crisaborole Impurity 67 (CAS CATO-C4X-202167)
- Crisaborole impurity 121 (CAS CATO-C4X-2021121)
- Crisaborole Impurity 19 (CAS CATO-C4X-202119)
- Crisaborole Impurity 55 (CAS CATO-C4X-202155)
- Crisaborole impurity 120 (CAS CATO-C4X-2021120)
Recommended Standards
- Bromfenac Impurity 21 (CAS CATO-C4X-200221)
- Bromazepam EP Impurity D (CAS 77616-97-8)
- Bromfenac Impurity 20 (CAS CATO-C4X-200220)
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- Fingolimod Impurity 14 (CAS 162361-49-1)
- Ceritinib Impurity 87 (CAS 2976-70-7（free base))
- Levamisole EP Impurity A (CAS 32190-34-4)
- (R)-4-tert-Butyl 3-methyl 3-methylmorpholine-3,4-dicarboxylate (CAS 1956437-89-0)
- 1-Oxa-8-azaspiro[4.5]decane, 2,2-dimethyl- (CAS 374794-94-2)
- Sodium bisulfite (CAS 7631-90-5)
- (2R,3R)-1-Cbz-2-methylpiperidine-3-carboxylic Acid (CAS 1932256-61-5)
- 2,4-Dimethylphenol (CAS 105-67-9)
- 2-(4-(Trifluoromethyl)phenoxy)propan-1-amine hydrochloride (CAS 1260651-23-7)
- Insulin Degludec Impurity 10 (CAS CATO-C4X-215710)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com