Ruxolitinib Impurity 128 CAS CATO-C4X-2058128
| CAS No. | CATO-C4X-2058128 |
| Molecular Formula | C15H16N6O3 |
| Molecular Weight | 328.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ruxolitinib Impurity 128 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Ruxolitinib Impurity 128 (CAS CATO-C4X-2058128), a pharmacopoeial impurity reference standard (molecular formula C15H16N6O3, MW 328.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Ruxolitinib Impurity 128 (C15H16N6O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ruxolitinib Impurity 128 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H16N6O3 |
| Molecular Weight | 328.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Ruxolitinib Standards
- Ruxolitinib Impurity 1 (CAS 2606144-44-7)
- Ruxolitinib Impurity 169 (CAS CATO-C4X-2058169)
- Ruxolitinib Impurity 3 (CAS 2102675-40-9)
- Ruxolitinib Impurity 77 (CAS 3016399-21-3)
- Ruxolitinib Impurity 170 (CAS CATO-C4X-2058170)
- Ruxolitinib Impurity 2 (CAS 2102675-42-1)
- Ruxolitinib Impurity 27 (CAS CATO-C4X-205827)
- Ruxolitinib Impurity 6 (CAS 1911644-32-0)
Recommended Standards
- N1-Cycloheptyl-N2-(4-(trifluoromethyl)phenyl)oxalamide (CAS 941963-12-8)
- 1-{4-[(methoxycarbonyl)amino]benzenesulfonyl}pyrrolidine-2-carboxylic acid (CAS 1008946-47-1)
- Ethyl 2-(3-{[(1-phenyl-1H-1,2,4-triazol-3-yl)oxy]methyl}-1H-1,2,4-triazol-5-yl)acetate (CAS 338756-09-5)
- 1-[(2-methyl-5-nitrophenyl)sulfonyl]piperidine-2-carboxylic acid (CAS 1009548-94-0)
- Delafloxacin Impurity 23 (CAS CATO-C4X-263723)
- Lecithin Impurity 3 (CAS 1176589-68-6)
- Tofacitinib Impurity 245 (CAS CATO-C4X-1079245)
- Ethyl 2-(2-(((benzyloxy)carbonyl)amino)acetamido)acetate (CAS 3005-87-6)
- (Rp)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (4-(trifluoromethyl)phenyl) phenylphosphonate (CAS 1463876-01-8)
- 2,5-DIchloro-pyridin-4-ylamine hydrochloride (CAS 1951439-45-4)
- 2-(1,1-Difluoroethyl)benzonitrile (CAS 1706430-09-2)
- CAY10606 (CAS 1159576-98-3)
- n-Ethyl-N-(pyrrolidin-3-yl)tetrahydrofuran-3-carboxamide (CAS 1248928-19-9)
- Peptide 439 (CAS CATO-CPTD788439)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com