Avatrombopag Impurity 88 HCl CAS CATO-C4X-223488
| CAS No. | CATO-C4X-223488 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 191.66 g/mol gives Avatrombopag Impurity 88 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Avatrombopag Impurity 88 HCl (CAS CATO-C4X-223488), a pharmacopoeial impurity reference standard (molecular formula C8H13NO2HCl, MW 191.66 g/mol) used for the identification and quantification of trace impurities in APIs.
Avatrombopag Impurity 88 HCl (C8H13NO2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Avatrombopag Impurity 88 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 HCl |
| Molecular Weight | 191.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Avatrombopag Standards
- Avatrombopag Impurity 31 (CAS 1126-09-6)
- Avatrombopag Impurity 52 (CAS 1224935-95-8)
- Avatrombopag Impurity 20 (CAS 123971-45-9)
- Avatrombopag Impurity 43 (CAS 1268118-96-2)
- Avatrombopag Impurity 5 (CAS 1290121-42-4)
- Avatrombopag Impurity 24 (CAS 1534575-19-3)
- Avatrombopag Impurity 92 (CAS 160114-74-9)
- Avatrombopag Impurity 37 (CAS 17766-28-8)
Recommended Standards
- Dyclonine Impurity 12 (CAS 91763-92-7)
- Cefuroxime Axetil Impurity 8 (CAS 26395-99-3)
- Tamsulosin EP Impurity E (CAS 105764-07-6)
- 4-((1,3-Dioxoisoindolin-2-yl)methyl)-N-(4-methoxyphenyl)benzenesulfonamide (CAS 955298-15-4)
- 3-Chloro-5-hydroxy-4-iodobenzoic acid (CAS 2385054-24-8)
- 3-[4-(tert-butyl)phenyl]-5-{2-[5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]vinyl}-1,2,4-oxadiazole (CAS 648859-80-7)
- 2,6-Diiodo-4-methylphenol (CAS 2432-18-0)
- 5-(Thiophen-2-yl)furan-2-carboxylic acid (CAS 886505-79-9)
- Fenitrooxon-d6 (O,O-dimethyl-d6) (CAS 1185155-54-7)
- Semaglutide impurity 233 (CAS CATO-C4X-2226233)
Why CATO?
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