Avatrombopag Impurity 24 CAS 1534575-19-3
| CAS No. | 1534575-19-3 |
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Avatrombopag Impurity 24 (CAS 1534575-19-3) is a certified pharmaceutical impurity reference standard with the molecular formula C7H4BrClN2S2 and a molecular weight of 295.61 g/mol.
The molecular framework of Avatrombopag Impurity 24 (C7H4BrClN2S2) is characterized by a nitrile group, sulfur-containing functionality, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Avatrombopag Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag impurity 134 (CAS CATO-C4X-2234134)
- Avatrombopag Impurity 38 (CAS 2161380-87-4)
- Avatrombopag Impurity 43 (CAS 1268118-96-2)
- Avatrombopag Impurity 144 (CAS CATO-C4X-2234144)
- Avatrombopag impurity 125 (CAS CATO-C4X-2234125)
- Avatrombopag Impurity 18 (CAS 958457-83-5)
- Avatrombopag Impurity 72 (CAS CATO-C4X-223472)
- Avatrombopag Impurity 50 (CAS CATO-C4X-223450)
Recommended Standards
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)ethanamine (CAS 2096333-72-9)
- 5-Bromo-4-chloro-2-(methylthio)thieno[2,3-d]pyrimidine (CAS 1823552-34-6)
- 3-(4-Chloro-2-fluoro-5-methoxyphenyl)-5-(trifluoromethyl)isoxazole (CAS 653569-96-1)
- 3-Chloro-2-((difluoromethyl)sulfonyl)-5-(trifluoromethyl)pyridine (CAS 1823183-18-1)
- Buspirone EP Impurity E (CAS 257877-43-3)
- Amisulpride EP Impurity G (CAS 148516-68-1)
- Granisetron EP Impurity A HCL (CAS 127472-42-8（free base）)
- N-(3-aminopropyl)-3,5-dimethylisoxazole-4-sulfonamide hydrochloride (CAS 1827894-21-2)
- Peramivir Impurity 68 (CAS CATO-C4X-183368)
- 2-Chloro-N-(2,5-diiodophenyl)propanamide (CAS 2137595-74-3)
- 3-(Oxan-4-yl)prop-2-enoic acid (CAS 856413-64-4)
- ethyl 4-[(2,4-difluorophenoxy)methyl]-5-methylisoxazole-3-carboxylate (CAS 938022-06-1)
- Methyl 5-benzoyl-2-methylthiazole-4-carboxylate (CAS 920113-32-2)
- Biotinyl-S6 Phosphate Acceptor Peptide trifluoroacetate salt (CAS 1815618-12-2)
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