Avatrombopag Impurity 43 CAS 1268118-96-2
| CAS No. | 1268118-96-2 |
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Avatrombopag Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Avatrombopag Impurity 43 (CAS 1268118-96-2), a pharmacopoeial impurity reference standard (molecular formula C7H4BrClN2S2, MW 295.61 g/mol) used for the identification and quantification of trace impurities in APIs.
Avatrombopag Impurity 43 (C7H4BrClN2S2) contains a nitrile group, sulfur-containing functionality, chlorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C7H4BrClN2S2 |
| Molecular Weight | 295.61 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag impurity 134 (CAS CATO-C4X-2234134)
- Avatrombopag Impurity 24 (CAS 1534575-19-3)
- Avatrombopag Impurity 38 (CAS 2161380-87-4)
- Avatrombopag Impurity 144 (CAS CATO-C4X-2234144)
- Avatrombopag impurity 125 (CAS CATO-C4X-2234125)
- Avatrombopag Impurity 18 (CAS 958457-83-5)
- Avatrombopag Impurity 72 (CAS CATO-C4X-223472)
- Avatrombopag Impurity 50 (CAS CATO-C4X-223450)
Recommended Standards
- 3-(4-Chloro-2-fluoro-5-methoxyphenyl)-5-(trifluoromethyl)isoxazole (CAS 653569-96-1)
- 3-(4-Chlorophenyl)-3-(2,2,2-trifluoroacetamido)propanoic acid (CAS 117291-25-5)
- 4-((2-Chloro-5-(trifluoromethyl)phenyl)amino)-4-oxobutanoic acid (CAS 199803-99-1)
- N-(2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)ethanamine (CAS 2096333-72-9)
- Blonanserin Impurity 18 (CAS 132810-93-6(free base))
- Adapalene Impurity 22 (CAS CATO-C4X-180922)
- Palbociclib Impurity 69 (CAS 6163-63-9)
- 2-[4-(2-Amino-6-chlorophenyl)-1-piperazinyl]-1-ethanol (CAS 1155523-02-6)
- Methyl 1,3-dioxo-1,3-dihydroisobenzofuran-5-carboxylate (CAS 2902-64-9)
- (Z)-3-(Dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine Maleate (CAS 147365-12-6)
- N-(3-Chloro-4-methylphenyl)-5-methylisoxazole-4-carboxamide (CAS 61643-43-4)
- N,N,2,2,3,3-Hexamethylcyclopropanecarboxamide (CAS 53066-20-9)
- 7-methoxy-1H-benzimidazole-5-carboxylic acid (CAS 1195408-40-2)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
Why CATO?
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