Ponatinib Impurity 17 CAS CATO-C4X-226917
| CAS No. | CATO-C4X-226917 |
| Molecular Formula | C37H32F6N6O |
| Molecular Weight | 690.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ponatinib Impurity 17 (CAS CATO-C4X-226917, C37H32F6N6O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Ponatinib Impurity 17 (C37H32F6N6O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ponatinib Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C37H32F6N6O |
| Molecular Weight | 690.68 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related Ponatinib Standards
- Ponatinib Metabolite AP-24567 N-Glucuronide (Amadori Rearrangement Product) (CAS CATO-C4X-226926)
- Ponatinib Impurity 58 (CAS CATO-C4X-226958)
- Ponatinib Impurity 25 (CAS CATO-C4X-226925)
- Ponatinib Impurity 22 (CAS CATO-C4X-226922)
- Ponatinib Impurity 21 (CAS CATO-C4X-226921)
- Ponatinib Impurity 14 (CAS CATO-C4X-226914)
- Ponatinib Impurity 29 (CAS CATO-C4X-226929)
- Ponatinib Impurity 55 (CAS CATO-C4X-226955)
Recommended Standards
- Sitagliptin Impurity 103 (CAS CATO-C4X-1144103)
- N-Benzylpentafluoropropionamide (CAS 1799-75-3)
- Cefpirome Impurity 22 (CAS CATO-C4X-120722)
- Vonoprazan Fumarate Impurity 118 (CAS CATO-C4X-1020118)
- Torasemide Impurity 23 (CAS CATO-C4X-183623)
- Loxoprofen Impurity 38 (CAS CATO-C4X-148838)
- rac-Pregabalin EP Impurity A (CAS 61312-87-6)
- 2-bromo-6-hydroxybenzoic acid (CAS 38876-70-9)
- Tert-butyl (3aS,6aS)-3a-methoxyhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate (CAS 1428776-61-7)
- (4-Chloro-3,5-dimethylfuran-2-yl)(phenyl)methanol (CAS 1443305-45-0)
- Niclosamide Impurity 2 (CAS 16739-20-1)
- 5-[(4-fluorophenyl)methyl]-1,2,4-thiadiazol-3-amine (CAS 1343928-91-5)
- (Tetrahydro-2H-pyran-3-yl)hydrazine hydrochloride (CAS 1221885-56-8)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
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