Fluocinolone Acetonide impurity 21 CAS CATO-C4X-238121
| CAS No. | CATO-C4X-238121 |
| Molecular Formula | C21H26F2O6 |
| Molecular Weight | 412.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Fluocinolone Acetonide impurity 21 (CAS CATO-C4X-238121) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26F2O6 and a molecular weight of 412.42 g/mol.
Fluocinolone Acetonide impurity 21 (C21H26F2O6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H26F2O6 |
| Molecular Weight | 412.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide impurity 22 (CAS CATO-C4X-238122)
- Fluocinolone Acetonide EP Impurity C (CAS 807-38-5)
- Fluocinolone Acetonide Impurity N2 (CAS 3830-58-8)
- Fluocinolone Acetonide Impurity 43 (CAS 3802-45-7)
- Fluocinolone Acetonide EP Impurity F (CAS 1526-01-8)
- Fluocinolone Acetonide Impurity 47 (CAS 389119-98-6)
- Fluocinolone Acetonide EP Impurity E (CAS 68352-03-4)
- Fluocinolone Acetonide Impurity 46 (CAS CATO-C4X-238146)
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- 2-(1-Aminoethyl)-4-methylthiazole-5-carboxylic acid (CAS 1017422-58-0)
- 7-Fluoro-2-methylimidazo[1,2-a]pyridine (CAS 1260812-67-6)
- 2-Cyano-N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide (CAS 98841-65-7)
- N-(4-(5,6,7,8-Tetrahydronaphthalen-2-yl)thiazol-2-yl)cyclohexanecarboxamide (CAS 684232-96-0)
- Clematoside S (CAS 72629-76-6)
- N-(4-Chloropyrimidin-2-yl)methanesulfonamide (CAS 1694010-55-3)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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