Fluocinolone Acetonide EP Impurity C CAS 807-38-5
| CAS No. | 807-38-5 |
| Molecular Formula | C21H26F2O6 |
| Molecular Weight | 412.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Fluocinolone Acetonide EP Impurity C meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Fluocinolone Acetonide EP Impurity C (CAS 807-38-5) is a certified pharmaceutical impurity reference standard with the molecular formula C21H26F2O6 and a molecular weight of 412.42 g/mol.
Fluocinolone Acetonide EP Impurity C (C21H26F2O6) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H26F2O6 |
| Molecular Weight | 412.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide impurity 21 (CAS CATO-C4X-238121)
- Fluocinolone Acetonide impurity 22 (CAS CATO-C4X-238122)
- Fluocinolone Acetonide Impurity N2 (CAS 3830-58-8)
- Fluocinolone Acetonide Impurity 43 (CAS 3802-45-7)
- Fluocinolone Acetonide EP Impurity F (CAS 1526-01-8)
- Fluocinolone Acetonide Impurity 47 (CAS 389119-98-6)
- Fluocinolone Acetonide EP Impurity E (CAS 68352-03-4)
- Fluocinolone Acetonide Impurity 46 (CAS CATO-C4X-238146)
Recommended Standards
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- Sulfasalazine impurity 14 (CAS 42753-55-9)
- PF-5081090 (CAS 1312473-63-4)
- Mitiglinide Impurity 7 (CAS 21307-97-1)
- Ledipasvir impurity 1 (CAS 134877-62-6)
- Dotinurad Impurity 61 (CAS 428458-98-4)
- Calciferol Impurity 4 (CAS 3270-02-8)
- Lithium hydrogen sulfate (CAS 13453-86-6)
- (R)-5-Phenyl-2-(pyrrolidin-2-yl)-1H-imidazole (CAS 1311255-08-9)
- (4R,4'R,5R,5'R)-2,2'-(2,3-Dhydro-1H-indene-2,2-diyl)bis(4,5-diphenyl-4,5-dihydrooxazole) (CAS 2757085-87-1)
- 1H-Pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 5334-23-6)
- 1-(4-Fluorophenyl)-1H-imidazole 99% 1-(4-Fluorophenyl)imidazole 1-Fluoro-4-(1H-imidazol-1-yl)benzene 21441-24-7 (CAS 21441-24-7)
- Insulin Degludec Impurity 19 (CAS CATO-C4X-215719)
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