Fluocinolone Acetonide Impurity 47 CAS 389119-98-6
| CAS No. | 389119-98-6 |
| Molecular Formula | C22H28F2O4 |
| Molecular Weight | 394.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Fluocinolone Acetonide Impurity 47 (CAS 389119-98-6), a pharmacopoeial impurity reference standard (molecular formula C22H28F2O4, MW 394.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Fluocinolone Acetonide Impurity 47 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 394.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Fluocinolone Acetonide Impurity 47 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28F2O4 |
| Molecular Weight | 394.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide impurity 21 (CAS CATO-C4X-238121)
- Fluocinolone Acetonide impurity 22 (CAS CATO-C4X-238122)
- Fluocinolone Acetonide EP Impurity C (CAS 807-38-5)
- Fluocinolone Acetonide Impurity N2 (CAS 3830-58-8)
- Fluocinolone Acetonide impurity 118 (CAS CATO-C4X-238118)
- Fluocinolone Acetonide Impurity 43 (CAS 3802-45-7)
- Fluocinolone Acetonide EP Impurity F (CAS 1526-01-8)
- Fluocinolone Acetonide EP Impurity E (CAS 68352-03-4)
Recommended Standards
- Cefixime Impurity 86 (CAS CATO-C4X-113986)
- Difluocortolone (CAS 2607-06-9)
- Ilaprazole Impurity 169 (CAS CATO-C4X-1130169)
- CI Disperse Red 179 (CAS 16586-42-8)
- Estradiol Impurity 6 (CAS 1423-97-8)
- Cefepime impurity 37 (CAS CATO-C4X-119337)
- Palbociclib Impurity 22 (CAS 1376615-91-6)
- 4-[3-(2-Aminoethyl)piperidin-1-yl]butan-1-ol (CAS 1339644-48-2)
- 2-(4-(4-Acetylphenyl)piperazine-1-carbonyl)-5-(benzyloxy)-4H-pyran-4-one (CAS 1021024-06-5)
- 3-(1-Naphthalenyloxy)-1,2-propanediol-d5 (CAS 69533-57-9)
- 3-{2-[(2-Methyl-2-propenyl)oxy]ethyl}piperidinehydrochloride (CAS 1220018-21-2)
- Methyl 2-(3-methylpyridin-2-yl)acetate (CAS 1092477-78-5)
- 2,3,4,8,9-Pentachlorodibenzofuran mixed congeners (CAS 67517-48-0)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
Why CATO?
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