Fluocinolone Acetonide Impurity 43 CAS 3802-45-7
| CAS No. | 3802-45-7 |
| Molecular Formula | C23H27FO6 |
| Molecular Weight | 418.46 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 418.46 g/mol gives Fluocinolone Acetonide Impurity 43 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Fluocinolone Acetonide Impurity 43 (CAS 3802-45-7, C23H27FO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Fluocinolone Acetonide Impurity 43 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 418.46 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fluocinolone Acetonide Impurity 43 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H27FO6 |
| Molecular Weight | 418.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide EP Impurity F (CAS 1526-01-8)
- Fluocinolone Acetonide Impurity N2 (CAS 3830-58-8)
- Fluocinolone Acetonide impurity 21 (CAS CATO-C4X-238121)
- Fluocinolone Acetonide impurity 22 (CAS CATO-C4X-238122)
- Fluocinolone Acetonide EP Impurity C (CAS 807-38-5)
- Fluocinolone Acetonide EP Impurity E (CAS 68352-03-4)
- Fluocinolone Acetonide Impurity 46 (CAS CATO-C4X-238146)
- Fluocinolone Acetonide EP Impurity B (CAS 65751-34-0)
Recommended Standards
- Beraprost Impurity 25 (CAS CATO-C4X-218425)
- Phenylbis(2,4,6-trimethylbenzoyl)phosphine Oxide (CAS 162881-26-7)
- Pitavastatin Impurity 108 (CAS CATO-C4X-1037108)
- N-(4-Acetamidophenyl)-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105224-43-8)
- Folic Acid EP Impurity D (CAS 119-24-4)
- Benidipine Impurity 71 (CAS CATO-C4X-112071)
- Encorafenib Impurity 6 (CAS CATO-C4X-32496)
- N-(5-(5-Bromothiophen-2-yl)-1,3,4-oxadiazol-2-yl)-5-methylisoxazole-3-carboxamide (CAS 1021132-07-9)
- Ceftolozane Impurity 37 (CAS CATO-C4X-240637)
- 1-Ethyl-6-methoxyquinolin-4(1H)-one (CAS 127286-12-8)
- 2-((9-Ethyl-9H-carbazol-3-yl)amino)-2-oxoethyl 2-(imidazo[2,1-b]thiazol-6-yl)acetate (CAS 438599-31-6)
- 4-acetyl-N-[(5-chloro-2-methylphenyl)methyl]-3-ethyl-5-methyl-1H-pyrrole-2-carboxamide (CAS 1797582-48-9)
- [2-(hydroxymethyl)spiro[3.3]heptan-2-yl]methanol (CAS 93225-04-8)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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