Venetoclax Impurity 136 CAS CATO-C4X-2495136

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2495136
Molecular FormulaC16H27BN2O2Si
Molecular Weight318.29 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Venetoclax Impurity 136 CAS CATO-C4X-2495136 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 318.29 g/mol gives Venetoclax Impurity 136 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Venetoclax Impurity 136 (CAS CATO-C4X-2495136), a pharmacopoeial impurity reference standard (molecular formula C16H27BN2O2Si, MW 318.29 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C16H27BN2O2Si, Venetoclax Impurity 136 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 318.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Venetoclax Impurity 136 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H27BN2O2Si
Molecular Weight318.29 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2

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