Venetoclax Impurity 138 CAS CATO-C4X-2495138
| CAS No. | CATO-C4X-2495138 |
| Molecular Formula | C19H27ClN2 |
| Molecular Weight | 318.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Venetoclax Impurity 138.
Venetoclax Impurity 138 (CAS CATO-C4X-2495138) is a certified pharmaceutical impurity reference standard with the molecular formula C19H27ClN2 and a molecular weight of 318.88 g/mol.
Venetoclax Impurity 138 (C19H27ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Venetoclax Impurity 138 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H27ClN2 |
| Molecular Weight | 318.88 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
- Venetoclax Impurity 136 (CAS CATO-C4X-2495136)
- Venetoclax Impurity 1 (CAS 1228779-96-1)
- Venetoclax Impurity 102 (CAS CATO-C4X-2495102)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- Venetoclax Impurity 117 (CAS CATO-C4X-2495117)
- Venetoclax Impurity 123 (CAS CATO-C4X-2495123)
- Venetoclax Impurity 90 (CAS CATO-C4X-249590)
- Venetoclax Impurity 72 (CAS 2007920-25-2)
Recommended Standards
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- 1-Bromo-2,4-difluoro-3-iodobenzene (CAS 1208075-99-3)
- Mianserin Impurity 124 (CAS CATO-C4X-1369124)
- Rilpivirine Impurity 1 HCl (CAS 500287-94-5(free base))
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- 4-Nitro-1-phenyl-1H-pyrazole-3-carboxylic acid (CAS 701917-03-5)
- [2-(7-Ethylimidazo[1,2-a]pyridin-2-yl)ethyl]aminedihydrochloride (CAS 1332528-54-7)
- O-(4-(2-((4-methoxyphenyl)thio)acetyl)-2,6-dimethylphenyl) dimethylcarbamothioate (CAS 866136-16-5)
- (Prop-2-yn-1-yl)(quinolin-2-ylmethyl)amine (CAS 1042791-56-9)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com