Venetoclax Impurity 56 CAS CATO-C4X-249556
| CAS No. | CATO-C4X-249556 |
| Molecular Formula | C33H35ClN4O4 |
| Molecular Weight | 587.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Venetoclax Impurity 56 (CAS CATO-C4X-249556, C33H35ClN4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Venetoclax Impurity 56 (C33H35ClN4O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Venetoclax Impurity 56 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C33H35ClN4O4 |
| Molecular Weight | 587.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Venetoclax Standards
- Venetoclax Impurity 142 (CAS CATO-C4X-2495142)
- Venetoclax Impurity 41 (CAS CATO-C4X-249541)
- Venetoclax Impurity 81 (CAS CATO-C4X-249581)
- Venetoclax Impurity 51 (CAS CATO-C4X-249551)
- Venetoclax Impurity 27 (CAS CATO-C4X-249527)
- Venetoclax Impurity 67 (CAS CATO-C4X-249567)
- Venetoclax Impurity 65 (CAS CATO-C4X-249565)
- Venetoclax Impurity 43 (CAS CATO-C4X-249543)
Recommended Standards
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- Lithium Bis(nonafluorobutanesulfonyl)imide (CAS 119229-99-1)
- Eldecalcitol Impurity 9 (CAS 200636-42-6)
- Cilastatin Impurity 21 (CAS 107872-23-1)
- Clofazimine Impurity 23 (CAS CATO-C4X-207123)
- Propofol Impurity 49 (CAS CATO-C4X-147349)
- 6-(1-Aminoethyl)-8-fluoro-3,4-dihydroquinolin-2(1H)-one hydrochloride (CAS 1956386-24-5)
- (1S)-1-cycloheptylethan-1-amine hydrochloride (CAS 177859-53-9)
- 2,7-Oxepanedione (CAS 2035-75-8)
- 6,6-difluoro-1,4-diazepane;dihydrochloride (CAS 1956307-23-5)
- Pemafibrate Impurity 27 (CAS CATO-C4X-290327)
- Isobutyl 2-aminobenzo[d]thiazole-6-carboxylate (CAS 890092-79-2)
- Liraglutide Impurity 22 (CAS 536721-25-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com