Venetoclax Impurity 133 CAS CATO-C4X-2495133
| CAS No. | CATO-C4X-2495133 |
| Molecular Formula | C18H25ClN2 |
| Molecular Weight | 304.86 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Venetoclax Impurity 133 (C18H25ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 304.86 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Venetoclax Impurity 133 (CAS CATO-C4X-2495133), a pharmacopoeial impurity reference standard (molecular formula C18H25ClN2, MW 304.86 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Venetoclax Impurity 133 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H25ClN2 |
| Molecular Weight | 304.86 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
- Venetoclax Impurity 1 (CAS 1228779-96-1)
- Venetoclax Impurity 102 (CAS CATO-C4X-2495102)
- Venetoclax Impurity 103 (CAS CATO-C4X-2495103)
- Venetoclax Impurity 117 (CAS CATO-C4X-2495117)
- Venetoclax Impurity 123 (CAS CATO-C4X-2495123)
- Venetoclax Impurity 90 (CAS CATO-C4X-249590)
- Venetoclax Impurity 136 (CAS CATO-C4X-2495136)
- Venetoclax Impurity 138 (CAS CATO-C4X-2495138)
Recommended Standards
- (R)-2-((tert-butyldimethylsilyl)oxy)-1-(4-chloro-3-fluorophenyl)ethanol (CAS 1395078-43-9)
- (3-(2-Iodoacetamido)phenyl)boronic acid (CAS 87199-19-7)
- Chlorpromazine EP Impurity D (CAS 1225-64-5)
- 2,6-Dibromo-4-(trifluoromethyl)pyridine (CAS 1000152-84-0)
- Sildenafil EP Impurity C (CAS 139755-91-2)
- Verapamil Impurity 39 (CAS 31910-93-7)
- Avibactam Impurity 148 (CAS 2089462-91-7)
- butyl 1-butylpiperidine-2-carboxylate (CAS 86200-58-0)
- 4-Isonicotinoylmorpholine-3-carboxylic acid (CAS 1483011-96-6)
- 2-Ethoxy-6-methylpyrimidin-4-ol (CAS 55996-04-8)
- 2'-Bromo-2,6-dimethoxybiphenyl 2'-bromo-2,6-dimethoxy-1,1'-Biphenyl 755017-61-9 A9612 (CAS 755017-61-9)
- Methyl 4-bromoquinoline-2-carboxylate (CAS 139896-91-6)
- 2-([1-(3-Methylphenyl)-1h-tetrazol-5-yl]thio)propanoic acid (CAS 917217-91-5)
- Semaglutide impurity 286 (CAS CATO-C4X-2226286)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com