Resmetirom Impurity 49 CAS CATO-C4X-291249
| CAS No. | CATO-C4X-291249 |
| Molecular Formula | C19H19Cl3N6O4 |
| Molecular Weight | 501.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Resmetirom Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Resmetirom Impurity 49 (CAS CATO-C4X-291249) is a certified pharmaceutical impurity reference standard with the molecular formula C19H19Cl3N6O4 and a molecular weight of 501.75 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Resmetirom Impurity 49 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 501.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C19H19Cl3N6O4 |
| Molecular Weight | 501.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Resmetirom Standards
- Resmetirom impurity 60 (CAS 2403724-53-6)
- Resmetirom impurity 89 (CAS CATO-C4X-291289)
- Resmetirom Impurity 38 (CAS CATO-C4X-291238)
- Resmetirom impurity 113 (CAS CATO-C4X-2912113)
- Resmetirom impurity 85 (CAS CATO-C4X-291285)
- Resmetirom impurity 110 (CAS CATO-C4X-2912110)
- Resmetirom impurity 120 (CAS CATO-C4X-2912120)
- Resmetirom impurity 125 (CAS CATO-C4X-2912125)
Recommended Standards
- N-Boc-(+/-)-4-(4-{[tert-butyl(diphenyl)silyl]oxy}-phenyl)-3-amino-1-buten (CAS 1379812-37-9)
- 2,6-Dibromo-4-(2,6-dibromophenoxy)phenol (CAS 1622183-96-3)
- Avasimibe (CAS 166518-60-1)
- 3,3',5,5'-Tetrabromo-[1,1'-biphenyl]-2,2'-diol (CAS 21987-62-2)
- Testosterone Impurity 15 (CAS 1311972-85-6)
- Atosiban Impurity 7 (CAS CATO-C4X-22937)
- Relugolix Impurity 30 (CAS CATO-C4X-242930)
- 6108-23-2 ZQS5S890B6 Lithium formate monohydrate UNII-ZQS5S890B6 Formic acid, lithium salt, monohydrate Lithium formate monohydrate [MI] Monolithium formate monohydrate (CAS 6108-23-2)
- (2S,3S)-2-Methylpyrrolidin-3-ol (CAS 664364-48-1)
- 7-Bromo-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine (CAS 1245646-89-2)
- Oxymetazoline Impurity 16 (CAS CATO-C4X-172316)
- Apremilast Impurity 3 (CAS 1802246-60-1)
- Lidocaine Impurity 69 (CAS CATO-C4X-167969)
- Urotensin II-Related Peptide (human, mouse, rat) (CAS 342878-90-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com