Abemaciclib Impurity 45 CAS CATO-C4X-293745
| CAS No. | CATO-C4X-293745 |
| Molecular Formula | C39H51FN12 |
| Molecular Weight | 706.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abemaciclib Impurity 45.
CATO supplies Abemaciclib Impurity 45 (CAS CATO-C4X-293745), a pharmacopoeial impurity reference standard (molecular formula C39H51FN12, MW 706.90 g/mol) used for the identification and quantification of trace impurities in APIs.
Abemaciclib Impurity 45 (C39H51FN12) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abemaciclib Impurity 45 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C39H51FN12 |
| Molecular Weight | 706.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 12 |
Related Abemaciclib Standards
- Abemaciclib Impurity 46 (CAS CATO-C4X-293746)
- Abemaciclib impurity 119 (CAS CATO-C4X-2937119)
- Abemaciclib Impurity 58 (CAS CATO-C4X-293758)
- Abemaciclib Impurity 144 (CAS CATO-C4X-2937144)
- Abemaciclib Impurity 179 (CAS CATO-C4X-2937179)
- Abemaciclib Impurity 90 (CAS CATO-C4X-293790)
- Abemaciclib impurity 121 (CAS CATO-C4X-2937121)
- Abemaciclib Impurity 101 (CAS CATO-C4X-2937101)
Recommended Standards
- Febuxostat Impurity 113 (CAS CATO-C4X-1162113)
- 9,9′-Spirobi[9H-fluorene]-2,2′-diamine, N2,N2,N2′,N2′-tetrakis(4-methylphenyl)- (CAS 515833-76-8)
- CYtidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-(1-propynyl)- (CAS 869355-42-0)
- Ritonavir EP Impurity I (CAS 165315-26-4)
- Flumazenil EP Impurity B (CAS 131666-45-0)
- Ergocalciferol EP Impurity E (CAS 115-61-7)
- Tolvaptan Impurity 62 (CAS 2657689-30-8)
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- (5-((Pyridin-3-ylamino)methyl)furan-2-yl)methanol (CAS 1339127-64-8)
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- 2-(3-Methylbutanoyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (CAS 1103531-38-9)
- 2-(1-methylpyrrol-3-yl)ethanol (CAS 420787-50-4)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com