Abemaciclib Impurity 48 CAS CATO-C4X-293748
| CAS No. | CATO-C4X-293748 |
| Molecular Formula | C51H70N16 |
| Molecular Weight | 907.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Abemaciclib Impurity 48 (CAS CATO-C4X-293748, C51H70N16) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Abemaciclib Impurity 48 (C51H70N16) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Abemaciclib Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C51H70N16 |
| Molecular Weight | 907.21 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 25.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 16 |
Related Abemaciclib Standards
- Abemaciclib Impurity 101 (CAS CATO-C4X-2937101)
- Abemaciclib Impurity 172 (CAS CATO-C4X-2937172)
- Abemaciclib Impurity 144 (CAS CATO-C4X-2937144)
- Abemaciclib impurity 119 (CAS CATO-C4X-2937119)
- Abemaciclib Impurity 46 (CAS CATO-C4X-293746)
- Abemaciclib Impurity 45 (CAS CATO-C4X-293745)
- Abemaciclib Impurity 58 (CAS CATO-C4X-293758)
- Abemaciclib Impurity 179 (CAS CATO-C4X-2937179)
Recommended Standards
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