Abemaciclib Impurity 151 CAS CATO-C4X-2937151
| CAS No. | CATO-C4X-2937151 |
| Molecular Formula | C13H18N4O3 |
| Molecular Weight | 278.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 278.31 g/mol gives Abemaciclib Impurity 151 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Abemaciclib Impurity 151 (CAS CATO-C4X-2937151) is a certified pharmaceutical impurity reference standard with the molecular formula C13H18N4O3 and a molecular weight of 278.31 g/mol.
Abemaciclib Impurity 151 (C13H18N4O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Abemaciclib Impurity 151 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H18N4O3 |
| Molecular Weight | 278.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Abemaciclib Standards
- Abemaciclib (CAS CATO-C4X-2937131)
- Abemaciclib Impurity 174 (CAS CATO-C4X-2937174)
- Abemaciclib Impurity 128 (CAS CATO-C4X-2937128)
- Abemaciclib Impurity 130 (CAS CATO-C4X-2937130)
- Abemaciclib Impurity N4 (CAS 1231930-33-8)
- Abemaciclib impurity 110 (CAS CATO-C4X-2937110)
- Abemaciclib Impurity 124 (CAS 2380322-35-8)
- Abemaciclib Impurity 127 (CAS 2922910-91-4)
Recommended Standards
- Ozagrel Impurity 30 (CAS CATO-C4X-197130)
- Sudan Red G (CAS 1229-55-6)
- Nintedanib Impurity 9 (CAS 1038972-16-5)
- Bz-Arg-OH (CAS 154-92-7)
- Rapamycin Impurity 32 (CAS CATO-C4X-174632)
- Cefaclor Impurity 15 (CAS CATO-C4X-127015)
- Sildenafil Impurity 294 (CAS 200575-17-3)
- 3-{[(5-chloro-2-pyridyl)amino]methylidene}-1,1,1-trifluoropentane-2,4-dione (CAS 649665-65-6)
- 2-((3,5-Dimethyladamantan-1-yl)oxy)ethan-1-amine (CAS 887405-40-5)
- methyl 5-methyl-1H-indazole-7-carboxylate (CAS 1360945-87-4)
- N-BOC-4-Fluoro-3-trifluoromethylaniline (CAS 1072945-57-3)
- Azilsartan Impurity 100 (CAS CATO-C4X-1096100)
- 2-Cyclopropoxy-N-methyl-4-nitroaniline (CAS 1243350-11-9)
- Semaglutide impurity 44 (CAS CATO-C4X-222644)
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