Abemaciclib Impurity 97 CAS CATO-C4X-293797

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-293797
Molecular FormulaC15H14F2N4
Molecular Weight288.30 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Abemaciclib Impurity 97 CAS CATO-C4X-293797 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 288.30 g/mol gives Abemaciclib Impurity 97 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Abemaciclib Impurity 97 (CAS CATO-C4X-293797) is a certified pharmaceutical impurity reference standard with the molecular formula C15H14F2N4 and a molecular weight of 288.30 g/mol.

Abemaciclib Impurity 97 (C15H14F2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Abemaciclib Impurity 97 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H14F2N4
Molecular Weight288.30 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentF-containing
Nitrogen Atoms4

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