Dabrafenib Impurity 11 CAS CATO-C4X-303311
| CAS No. | CATO-C4X-303311 |
| Molecular Formula | C23H20ClF3N4O3S2 |
| Molecular Weight | 557.01 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dabrafenib Impurity 11 (CAS CATO-C4X-303311), a pharmacopoeial impurity reference standard (molecular formula C23H20ClF3N4O3S2, MW 557.01 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C23H20ClF3N4O3S2, Dabrafenib Impurity 11 contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 557.01 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H20ClF3N4O3S2 |
| Molecular Weight | 557.01 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Dabrafenib Standards
- Dabrafenib Impurity 16 (CAS CATO-C4X-303316)
- Dabrafenib Impurity 15 (CAS CATO-C4X-303315)
- Dabrafenib Impurity 36 (CAS CATO-C4X-303336)
- Dabrafenib Impurity N7 (CAS 1195768-23-0)
- Dabrafenib Impurity N2 (CAS 1195767-77-1)
- Dabrafenib Impurity 37 (CAS CATO-C4X-303337)
- Dabrafenib Impurity 38 (CAS 3052138-43-6)
- Dabrafenib Impurity 9 (CAS CATO-C4X-30339)
Recommended Standards
- Q203, 98% (CAS 1334719-95-7)
- Penfluridol Impurity 12 (CAS CATO-C4X-353812)
- Amlodipine Besylate EP Impurity H (CAS 318465-73-5)
- Tocopherol Impurity 14 (CAS CATO-C4X-119514)
- Procaterol Impurity 2 (CAS CATO-C4X-18102)
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- Alverine Impurity 14 HCl (CAS CATO-C4X-153914)
- 2-(3-(((Cyclopropylmethyl)amino)methyl)piperidin-1-yl)ethanamine (CAS 1353953-86-2)
- 6-(4-Fluorophenyl)-1,3-benzodioxole-5-carbaldehyde (CAS 927802-53-7)
- N'-(4-Fluorobenzo[d]thiazol-2-yl)benzo[d]thiazole-2-carbohydrazide (CAS 851978-81-9)
- 2-(Piperidin-1-yl)thiazole-4-carboxylic acid (CAS 952182-68-2)
- 1-(Isoxazol-3-yl)-1H-pyrrole-2-carbaldehyde (CAS 383135-78-2)
- N-[4-(4-Chloro-3-methylphenyl)-1,3-thiazol-2-yl]pyridin-3-amine (CAS 1023483-44-4)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com