Lotilaner Impurity 24 CAS CATO-C4X-325624
| CAS No. | CATO-C4X-325624 |
| Molecular Formula | C9H10O3S |
| Molecular Weight | 198.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Lotilaner Impurity 24 (CAS CATO-C4X-325624), a pharmacopoeial impurity reference standard (molecular formula C9H10O3S, MW 198.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Lotilaner Impurity 24 (C9H10O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10O3S |
| Molecular Weight | 198.24 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Sulfur Atoms | 1 |
Related Lotilaner Standards
- Lotilaner Impurity 22 (CAS CATO-C4X-325622)
- Lotilaner Impurity 21 (CAS CATO-C4X-325621)
- Lotilaner Impurity 4 (CAS CATO-C4X-32564)
- Lotilaner Impurity 20 (CAS CATO-C4X-325620)
- Lotilaner Impurity 23 (CAS CATO-C4X-325623)
- Lotilaner Impurity 29 (CAS 2226274-70-8)
- Lotilaner Impurity 7 (CAS CATO-C4X-32567)
- Lotilaner Impurity 15 (CAS CATO-C4X-325615)
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