Lotilaner Impurity 7 CAS CATO-C4X-32567
| CAS No. | CATO-C4X-32567 |
| Molecular Formula | C10H2Cl2F6O2 |
| Molecular Weight | 339.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Lotilaner Impurity 7 (CAS CATO-C4X-32567) is a certified pharmaceutical impurity reference standard with the molecular formula C10H2Cl2F6O2 and a molecular weight of 339.02 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Lotilaner Impurity 7 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 339.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H2Cl2F6O2 |
| Molecular Weight | 339.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Lotilaner Standards
- Lotilaner Impurity 29 (CAS 2226274-70-8)
- Lotilaner Impurity 15 (CAS CATO-C4X-325615)
- Lotilaner Impurity 20 (CAS CATO-C4X-325620)
- Lotilaner Impurity 23 (CAS CATO-C4X-325623)
- Lotilaner Impurity 4 (CAS CATO-C4X-32564)
- Lotilaner Impurity 21 (CAS CATO-C4X-325621)
- Lotilaner Impurity 14 (CAS CATO-C4X-325614)
- Lotilaner Impurity 8 (CAS CATO-C4X-32568)
Recommended Standards
- 5-Iodo-1H-indol-3-yl dihydrogen phosphate (CAS 7300-58-5)
- 2,7-Dibromo-9H-fluoren-4-amine (CAS 1785-09-7)
- 2-((3,5-Dibromo-2-methoxybenzyl)amino)ethan-1-ol (CAS 893603-45-7)
- 2-Amino-1,3-dibromofluorene (CAS 3405-09-2)
- Sodium Valproate EP Impurity K (CAS 5343-52-2)
- Fexofenadine Impurity 46 (CAS CATO-C4X-179446)
- Propetamphos Impurity 1 (CAS 99606-11-8)
- 3-(Isoxazol-3-yl)-1,1-dimethylurea (CAS 55807-89-1)
- 3-{4-[(4-Chlorophenyl)thio]-3-nitrophenyl}acrylic acid (CAS 175278-52-1)
- Cyclohexyl(phenyl)methanamine (CAS 23459-35-0)
- 3-(Trifluoromethyl)phenyl 2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetate (CAS 478065-82-6)
- 1-Fluoro-3-iodopropane (CAS 462-40-8)
- 2-(3-Bromophenyl)quinoline-4-carboxylic acid (CAS 298230-83-8)
- Semaglutide Impurity 167 (CAS CATO-C4X-2226167)
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