Aprepitant USP Related Compound A CAS 1148113-53-4
| CAS No. | 1148113-53-4 |
| Molecular Formula | C23H21F7N4O3 |
| Molecular Weight | 534.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C23H21F7N4O3, Aprepitant USP Related Compound A contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 534.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Aprepitant USP Related Compound A (CAS 1148113-53-4), molecular formula C23H21F7N4O3 and molecular weight 534.43 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Aprepitant USP Related Compound A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H21F7N4O3 |
| Molecular Weight | 534.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Aprepitant Standards
- Aprepitant (CAS 170729-80-3)
- Aprepitant Impurity 2 (CAS 1185502-97-9)
- Aprepitant Impurity 3 (CAS 172822-28-5)
- Aprepitant Impurity 4 (CAS 172822-29-6)
- Aprepitant Impurity 5 (CAS 1242175-40-1)
- Aprepitant Impurity 6 (CAS 170902-81-5)
- Aprepitant impurity 66 (CAS CATO-C4X-114166)
- Aprepitant Impurity 7 (CAS 1242175-34-3)
Recommended Standards
- Perfluorophenyl (((9H-fluoren-9-yl)methoxy)carbonyl)-D-glutaminate (CAS 200622-33-9)
- 5-[[(2S,3R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-one (CAS 221350-96-5)
- 2-((5-(5-Bromo-2-hydroxyphenyl)-4-(2,4-dimethylphenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyanophenyl)acetamide (CAS 875006-54-5)
- Luteoline-7-malonylglucoside (CAS 98767-38-5)
- DL-Arginine (CAS 7200-25-1)
- N-(Furan-2-ylmethyl)-5-methyl-1-(3-phenylbenzo[c]isoxazol-5-yl)-1H-1,2,3-triazole-4-carboxamide (CAS 950428-76-9)
- Fmoc-(R)-3-amino-4-(3,4-dichloro-phenyl)-butyric acid (CAS 269396-57-8)
- N-(2,2,2-trifluoroethyl)tetrahydrofuran-3-amine hydrochloride (CAS 1384427-96-6)
- (R)-3-Amino-2-azepanone (CAS 28957-33-7)
- N-(tert-Butyl)-3,5,6-trifluoropyridin-2-amine (CAS 189281-22-9)
- 2-((5-Methylisoxazol-3-yl)methylene)hydrazinecarboxamide (CAS 89727-83-3)
- 1-Bromo-4-[(2,2-diethoxyethyl)sulfanyl]benzene (CAS 96804-05-6)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-(2,3-dimethylphenoxy)-5,6,7,8-tetrahydroquinazoline (CAS 339019-02-2)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
Why CATO?
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