(3Z)-4-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}but-3-en-2-one CAS 1164455-16-6
| CAS No. | 1164455-16-6 |
| Molecular Formula | C18H12ClF3N2O |
| Molecular Weight | 364.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (3Z)-4-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}but-3-en-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (3Z)-4-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}but-3-en-2-one (CAS 1164455-16-6), a certified reference material (molecular formula C18H12ClF3N2O, MW 364.75 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, (3Z)-4-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-indol-3-yl}but-3-en-2-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF3N2O |
| Molecular Weight | 364.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-6-methyl-N-phenylpyrimidin-4-amine (CAS 1357147-49-9)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(1E)-(methoxyamino)methylidene]piperidine-4-carboxamide (CAS 303144-37-8)
- 4-Chloro-6-methyl-2-phenyl-5-(3-(trifluoromethyl)phenoxy)pyrimidine (CAS 680217-69-0)
- 2-Chloro-N-[5-(dimethylamino)-2-nitrophenyl]-5-nitrobenzamide (CAS 1079264-82-6)
- N-[5-Chloro-4-(trifluoromethyl)-2-pyridinyl]-2-[1-(hydroxyimino)ethyl]-5-thiazolecarboxamide (CAS 1095823-58-7)
- N-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)-4,N-dimethylbenzenesulfonamide (CAS 1311280-33-7)
- [({[(2-chloro-3-phenylprop-2-enylidene)amino]oxy}carbonyl)amino](2,6-difluorophenyl)methanone (CAS 680580-31-8)
- 1-(2-Chloro-6-fluorobenzyl)-3-(4-fluorobenzyl)imidazolidine-2,4,5-trione (CAS 341966-54-9)
Recommended Standards
- ethyl 4-[(2-chloro-3-pyridyl)oxy]-5,8-difluoroquinoline-3-carboxylate (CAS 245073-04-5)
- 3-(4-Chlorobenzenesulfonyl)-5-(trifluoromethyl)pyridine-2-carboxamide (CAS 338406-81-8)
- 1-Acetyl-N'-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperidine-4-carbohydrazide (CAS 439094-42-5)
- N-(2-chlorobenzyl)-2-(pyridin-2-yl)-6-(trifluoromethyl)pyrimidin-4-amine (CAS 338754-48-6)
- 2-Butyl-1H-indene (CAS 92013-12-2)
- Methyl methyl(phenyl)carbamate (CAS 28685-60-1)
- 2-Bromo-5-methylbenzene-1,4-diol (CAS 67289-05-8)
- 3-(4-aminophenoxy)propanoic acid (CAS 350699-65-9)
- Nafamostat Impurity 22 (CAS CATO-C4X-133222)
- (2E)-3-(3-Fluorophenyl)-1-(2-methylphenyl)prop-2-en-1-one (CAS 1354941-31-3)
- (E)-5-(2-(dimethylamino)vinyl)-3-(methylthio)isothiazole-4-carbonitrile (CAS 338402-77-0)
- 1-(1-Chloro-2,2-difluoroethyl)benzene (CAS 345-62-0)
- Ethyl 4-chloro-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate (CAS 1245645-25-3)
- Pheromone Biosynthesis Activating Neuropeptide (Helicoverpa assulta, Heliothis zea) (CAS 122071-54-9)
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