Dexamethasone Sodium Phosphate EP Impurity E CAS CATO-C4X-116529
| CAS No. | CATO-C4X-116529 |
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Dexamethasone Sodium Phosphate EP Impurity E (CAS CATO-C4X-116529), a pharmacopoeial impurity reference standard (molecular formula C22H30FO8P, MW 472.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Dexamethasone Sodium Phosphate EP Impurity E (C22H30FO8P) contains a flavonoid core, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.5, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 472.44 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Dexamethasone Sodium Phosphate EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H30FO8P |
| Molecular Weight | 472.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 108 (CAS CATO-C4X-1165108)
- Dexamethasone Impurity 109 (CAS CATO-C4X-1165109)
- Dexamethasone Impurity 117 (CAS CATO-C4X-1165117)
- Dexamethasone Impurity 128 (CAS CATO-C4X-1165128)
- Dexamethasone Sodium Phosphate EP Impurity C (CAS CATO-C4X-116522)
- Dexamethasone Sodium Phosphate Impurity B (CAS 360-63-4)
- Dexamethasone Sodium Phosphate EP Impurity D (CAS CATO-C4X-116528)
- Dexamethasone Sodium Phosphate EP Impurity F (CAS CATO-C4X-116530)
Recommended Standards
- Dexamethasone Phosphate (CAS 312-93-6)
- D-Homo B Derivative of Dexamethasone (CAS CATO-C4X-116552)
- Dexamethasone impurity 63 (CAS 1202001-99-7)
- Dexamethasone impurity 64 (CAS CATO-C4X-116564)
- Trelagliptin Impurity 10 (CAS CATO-C4X-104610)
- Loratadine EP Impurity 39 (CAS 609806-38-4)
- Cefixime Impurity 73 (CAS CATO-C4X-113973)
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- Semaglutide Impurity 130 (CAS 1188328-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com