Ticagrelor Impurity 111 CAS 1549834-66-3
| CAS No. | 1549834-66-3 |
| Molecular Formula | C7H11N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ticagrelor Impurity 111 (CAS 1549834-66-3, C7H11N3O2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ticagrelor Impurity 111 (C7H11N3O2SHCl) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 237.70 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Ticagrelor Impurity 111 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H11N3O2S HCl |
| Molecular Weight | 237.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 88 (CAS 1006376-61-9)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Ticagrelor Impurity 121 (CAS 1006614-49-8)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 113 (CAS 1156575-52-8)
- Ticagrelor impurity 161 (CAS 1157692-93-7)
- Ticagrelor Impurity 168 (CAS 1207276-00-3(free base))
Recommended Standards
- Upadacitinib Impurity 131 (CAS CATO-C4X-2405131)
- Ipragliflozin Impurity 12 (CAS CATO-C4X-188512)
- Imrecoxib Impurity 71 (CAS CATO-C4X-237971)
- tert-Butyl (1-ethynylcyclopropyl)carbamate (CAS 1268810-09-8)
- 4-(2-Amino-4-chlorophenyl)-2-piperazinone (CAS 926239-48-7)
- (9Z,12Z)-3-Hydroxy-2-(hydroxymethyl)propyl octadeca-9,12-dienoate (CAS 1470305-83-9)
- (5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methanol (CAS 1026796-39-3)
- 5-Ethynyl-2,2'-bipyridine (CAS 162318-34-5)
- 3-Phenylisoxazol-4-amine (CAS 23350-02-9)
- Semaglutide impurity 57 (CAS 2773558-06-6)
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