Everolimus Impurity N1 CAS 164162-36-1
| CAS No. | 164162-36-1 |
| Molecular Formula | C9H19F3O4SSi |
| Molecular Weight | 308.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Everolimus Impurity N1 (C9H19F3O4SSi) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Everolimus Impurity N1 (CAS 164162-36-1), a pharmacopoeial impurity reference standard (molecular formula C9H19F3O4SSi, MW 308.39 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Everolimus Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H19F3O4SSi |
| Molecular Weight | 308.39 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | -1.0 |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Everolimus Standards
- Everolimus Impurity 45 (CAS CATO-C4X-112245)
- Everolimus Impurity 9 (CAS 2607-52-5)
- Everolimus Impurity 28 (CAS 102229-10-7)
- Everolimus Impurity 2 (CAS 147438-30-0)
- Everolimus Impurity 18 (CAS 141392-23-6)
- Everolimus Impurity 15（Z&Emixture） (CAS 147438-27-5 (E-Isomer）)
- Everolimus Impurity 16 (CAS 147438-29-7)
- Everolimus Impurity 17 (CAS 253431-35-5)
Recommended Standards
- Tripentyl phosphate (CAS 2528-38-3)
- 2-Methyl-1-(3-(thiophen-2-yl)indeno[1,2-c]pyrazol-1(4H)-yl)propan-1-one (CAS 1024491-27-7)
- trans-tert-Butyl 4-(benzylamino)-3-fluoropiperidine-1-carboxylate (CAS 211108-52-0)
- 4-Methyl-N-(4-(p-tolyl)thiazol-2-yl)benzamide (CAS 103966-02-5)
- Olaparib Impurity 118 (CAS CATO-C4X-1135118)
- Haloperidol Impurity 39 (CAS 52669-92-8)
- Crisaborole impurity 151 (CAS CATO-C4X-2021151)
- (2|A,3|A,5|A,14xi,22r)-2,3,14,25-tetrahydroxy-6-oxocholest-7-en-22-yl dihydrogen phosphate 868-26-8 KST-1A8639 (CAS 868-26-8)
- 2-(4-Bromostyryl)-5-chloronicotinic acid (CAS 917942-73-5)
- Agmatine-d8 SulfateDISCONTINUED. Please see A601990 (CAS 909556-32-7)
- 5-Amino-4-(benzo[d]thiazol-2-yl)-1-phenyl-1H-pyrrol-3-ol (CAS 330857-84-6)
- 3-Hydroxychrysene (CAS 63019-39-6)
- 3,4,6,7-Tetrabromo-1,2-dichlorodibenzo[b,d]furan (CAS 107207-44-3)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com