Ticagrelor Impurity 128 CAS 1643378-59-9
| CAS No. | 1643378-59-9 |
| Molecular Formula | C9H9F2N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Ticagrelor Impurity 128 (C9H9F2NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Ticagrelor Impurity 128 (CAS 1643378-59-9, C9H9F2NHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 128 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9F2N HCl |
| Molecular Weight | 205.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity N40 (CAS 1006376-60-8)
- Ticagrelor Impurity 88 (CAS 1006376-61-9)
- Ticagrelor Impurity 152 (CAS 1006376-62-0)
- Ticagrelor Impurity 121 (CAS 1006614-49-8)
- Ticagrelor impurity 84（trans） (CAS 1006614-51-2)
- Ticagrelor Impurity 113 (CAS 1156575-52-8)
- Ticagrelor impurity 161 (CAS 1157692-93-7)
- Ticagrelor Impurity 168 (CAS 1207276-00-3(free base))
Recommended Standards
- Cefadroxil Impurity 36 (CAS CATO-C4X-122436)
- Bambuterol Impurity 11 (CAS CATO-C4X-274611)
- Isavuconazole impurity 66 (CAS CATO-C4X-1236166)
- 5-Butyl-1H-indole (CAS 1946799-48-9)
- Bis(isocyanocyclohexane)gold(1+) (CAS 49866-97-9)
- 2-(4-Chlorophenyl)pyrimidin-4-amine (CAS 114523-63-6)
- 5-Ethyl-4H-1,2,4-triazole-3-carboxylic acid (CAS 107469-68-1)
- 6-Bromo-8-methylquinoline HCl (CAS 1257665-18-1)
- 2-chloro-5-fluoro-[1,2,4]triazolo[1,5-a]pyridine (CAS 1935530-29-2)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com