Aprepitant Impurity 10 CAS 1651828-04-4
| CAS No. | 1651828-04-4 |
| Molecular Formula | C27H24F7NO3 |
| Molecular Weight | 543.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Aprepitant Impurity 10.
CATO supplies Aprepitant Impurity 10 (CAS 1651828-04-4), a pharmacopoeial impurity reference standard (molecular formula C27H24F7NO3, MW 543.47 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C27H24F7NO3, Aprepitant Impurity 10 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 543.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Aprepitant Impurity 10 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H24F7NO3 |
| Molecular Weight | 543.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Aprepitant Standards
- Aprepitant D4 (CAS 1133387-60-6)
- rac-Aprepitant-d4 (and enantiomer) (CAS CATO-C4X-114140)
- Aprepitant-13C2,d2 (Major) (CAS 1217676-37-3)
- Aprepitant Impurity 12 (CAS 172673-23-3)
- Aprepitant impurity 64 (CAS CATO-C4X-114164)
- Aprepitant (CAS 170729-80-3)
- Aprepitant USP Related Compound A (CAS 1148113-53-4)
- Aprepitant Impurity 2 (CAS 1185502-97-9)
Recommended Standards
- Bitopertin (CAS 845614-11-1)
- 6,7-Dichloro-1,4-bis(mesitylamino)anthracene-9,10-dione (CAS 18038-98-7)
- 2-Bromo-4-(3-(pyridin-2-yl)-1-trityl-1H-pyrazol-4-yl)pyridine (CAS 446880-83-7)
- 1-(2,4-Dinitrophenyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-histidine (CAS 83999-94-4)
- Posaconazole Impurity 6 (CAS 149809-42-7)
- Lomefloxacin Impurity 8 (CAS 195259-12-2)
- Maropitant Impurity 13 (CAS 155681-48-4)
- 1,3-dichloropentane (CAS 30122-12-4)
- 2,5-Dimethyl-4-(3-pyrrolinomethyl) benzophenone (CAS 898764-16-4)
- CHIR 124 (CAS 405168-58-3)
- Methyl 5-(3-chloro-4-fluorophenyl)-3-methyl-5-oxopentanoate (CAS 1443340-92-8)
- 1,2,5-Tribromo-3-fluorobenzene (CAS 2839-37-4)
- 1-(3-(3-Methyl-1,2,4-oxadiazol-5-yl)pyridin-2-yl)piperidin-4-amine dihydrochloride (CAS 1239748-54-9)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com