Chlortalidone EP Impurity F CAS 1796929-84-4
| CAS No. | 1796929-84-4 |
| Molecular Formula | C28H19Cl2N3O8S2 |
| Molecular Weight | 660.50 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Chlortalidone EP Impurity F (CAS 1796929-84-4), a pharmacopoeial impurity reference standard (molecular formula C28H19Cl2N3O8S2, MW 660.50 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Chlortalidone EP Impurity F (C28H19Cl2N3O8S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Chlortalidone EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H19Cl2N3O8S2 |
| Molecular Weight | 660.50 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Chlortalidone Standards
- Chlortalidone EP Impurity I (CAS 2514668-27-8)
- Chlortalidone Impurity 6 (CAS 68592-11-0)
- Chlortalidone EP Impurity C (CAS 92874-73-2)
- Chlortalidone EP Impurity D (CAS 1369995-36-7)
- Chlortalidone Sulfochloro Impurity (CAS 68592-12-1)
- Chlortalidone EP Impurity A (CAS 345930-32-7)
- Chlortalidone EP Impurity B (CAS 5270-74-6)
- Chlortalidone Impurity 4 (CAS 118-04-7)
Recommended Standards
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- tert-Butyl 4-(aminomethyl)-4-(2-ethoxy-2-oxoethyl)piperidine-1-carboxylate (CAS 2104409-60-9)
- [3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methanol (CAS 926242-11-7)
- Hexapeptide-10 (CAS 146439-94-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com