Cinacalcet Impurity 46 CAS 2062-25-1
| CAS No. | 2062-25-1 |
| Molecular Formula | C10H7F3O2 |
| Molecular Weight | 216.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Cinacalcet Impurity 46 (C10H7F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 216.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Cinacalcet Impurity 46 (CAS 2062-25-1) is a certified pharmaceutical impurity reference standard with the molecular formula C10H7F3O2 and a molecular weight of 216.16 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cinacalcet Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7F3O2 |
| Molecular Weight | 216.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Cinacalcet Standards
- Cinacalcet Impurity 38 (CAS 67801-07-4)
- Cinacalcet Impurity 45 (CAS 16642-92-5)
- Cinacalcet Impurity 113 (CAS 67646-72-4)
- Cinacalcet Impurity 3 (CAS 93040-58-5)
- Cinacalcet Impurity 7 (CAS 585-50-2)
- Cinacalcet Impurity 33 (CAS 94022-99-8)
- Cinacalcet Impurity 34 (CAS 53473-36-2)
- Cinacalcet Impurity 69 (CAS 114748-82-2)
Recommended Standards
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- Cefuroxime Axetil Impurity 12 (CAS CATO-C4X-143612)
- Moxidectin EP Impurity L (CAS 119718-45-5)
- Cholic Acid Impurity 83 (CAS CATO-C4X-116083)
- (3-(4,6-Dimethylpyrimidin-2-yl)phenyl)methanol (CAS 1349717-31-2)
- 3'-Formyl-[1,1'-biphenyl]-3-carbonitrile (CAS 400748-29-0)
- 7-Chloro-N,N-diethyl-4-nitrobenzo[c][1,2,5]oxadiazol-5-amine (CAS 257932-06-2)
- 1-(2-(Adamantan-1-yl)ethoxy)-3-(3-methylpiperidin-1-yl)propan-2-ol hydrochloride (CAS 479628-38-1)
- 2-Benzamido-2-phenylacetic acid (CAS 29670-63-1)
- 2,2-Dimethylpiperazine (CAS 84477-72-5)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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