Canagliflozin Impurity 51 CAS 2444540-10-5

Description

The occurrence of Canagliflozin Impurity 51 is closely related to sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Canagliflozin Impurity 51 (CAS 2444540-10-5), a pharmacopoeial impurity reference standard (molecular formula C18H14FIS, MW 408.27 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Canagliflozin Impurity 51 (C18H14FIS) is characterized by sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Canagliflozin Impurity 51 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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