Canagliflozin Impurity 54 CAS CATO-C4X-112354
| CAS No. | CATO-C4X-112354 |
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Canagliflozin Impurity 54 (CAS CATO-C4X-112354, C18H14FIS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H14FIS, Canagliflozin Impurity 54 contains sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 20 (CAS CATO-C4X-112320)
- Canagliflozin Impurity 27 (CAS 898566-17-1)
- Canagliflozin Impurity 51 (CAS 2444540-10-5)
- Canagliflozin Impurity 52 (CAS CATO-C4X-112352)
- Canagliflozin Impurity 53 (CAS CATO-C4X-112353)
- Canagliflozin Impurity 55 (CAS CATO-C4X-112355)
- Canagliflozin Impurity 76 (CAS 2952941-15-8)
- Canagliflozin Impurity 77 (CAS CATO-C4X-112377)
Recommended Standards
- Canagliflozin Impurity 80 (CAS CATO-C4X-112380)
- Canagliflozin Impurity 81 (CAS CATO-C4X-112381)
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- Canagliflozin Impurity 82 (CAS CATO-C4X-112382)
- Vinorelbine Impurity 19 (CAS CATO-C4X-264219)
- Levosimendan Impurity 32 (CAS CATO-C4X-130832)
- Ruxolitinib Impurity 47 (CAS CATO-C4X-205847)
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