Canagliflozin Impurity 53 CAS CATO-C4X-112353
| CAS No. | CATO-C4X-112353 |
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Canagliflozin Impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Canagliflozin Impurity 53 (CAS CATO-C4X-112353, C18H14FIS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H14FIS, Canagliflozin Impurity 53 contains sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 20 (CAS CATO-C4X-112320)
- Canagliflozin Impurity 27 (CAS 898566-17-1)
- Canagliflozin Impurity 51 (CAS 2444540-10-5)
- Canagliflozin Impurity 52 (CAS CATO-C4X-112352)
- Canagliflozin Impurity 54 (CAS CATO-C4X-112354)
- Canagliflozin Impurity 55 (CAS CATO-C4X-112355)
- Canagliflozin Impurity 76 (CAS 2952941-15-8)
- Canagliflozin Impurity 77 (CAS CATO-C4X-112377)
Recommended Standards
- 2-((2,4-Dichlorobenzyl)amino)-1,1-bis(4-fluorophenyl)ethanol (CAS 338771-37-2)
- Canagliflozin Impurity 80 (CAS CATO-C4X-112380)
- (5-Bromofuran-2-yl)(3-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1797174-09-4)
- Canagliflozin Impurity 81 (CAS CATO-C4X-112381)
- Radezolid Impurity 2 (CAS CATO-C4X-33622)
- Icariin Impurity 1 (CAS CATO-C4X-33511)
- Vonoprazan Impurity 43 (CAS 2169271-28-5)
- 1-(4-Chloro-2-fluorophenyl)cyclopropan-1-ol (CAS 1251152-65-4)
- Zoniporide (dihydrochloride) (CAS 241799-10-0)
- CAS CATO-C3D-1190 (CAS CATO-C3D-1190)
- Ethyl 2-ethyl-6-hydroxybenzoate (CAS 82064-77-5)
- α-D-Mannose-1-phosphate sodium salt (CAS 99749-54-9)
- tert-Butyl (S)-4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidine-1-carboxylate (CAS 2401894-43-5)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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