Canagliflozin Impurity 20 CAS CATO-C4X-112320
| CAS No. | CATO-C4X-112320 |
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Canagliflozin Impurity 20 (CAS CATO-C4X-112320, C18H14FIS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H14FIS, Canagliflozin Impurity 20 contains sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 408.27 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Canagliflozin Impurity 20 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14FIS |
| Molecular Weight | 408.27 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/I-containing |
| Sulfur Atoms | 1 |
Related Canagliflozin Standards
- Canagliflozin Impurity 27 (CAS 898566-17-1)
- Canagliflozin Impurity 51 (CAS 2444540-10-5)
- Canagliflozin Impurity 52 (CAS CATO-C4X-112352)
- Canagliflozin Impurity 53 (CAS CATO-C4X-112353)
- Canagliflozin Impurity 54 (CAS CATO-C4X-112354)
- Canagliflozin Impurity 55 (CAS CATO-C4X-112355)
- Canagliflozin Impurity 76 (CAS 2952941-15-8)
- Canagliflozin Impurity 77 (CAS CATO-C4X-112377)
Recommended Standards
- 2-((2,4-Dichlorobenzyl)amino)-1,1-bis(4-fluorophenyl)ethanol (CAS 338771-37-2)
- (5-Bromofuran-2-yl)(3-(5-(thiophen-3-yl)-1,3,4-oxadiazol-2-yl)piperidin-1-yl)methanone (CAS 1797174-09-4)
- (5-Bromofuran-2-yl)(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)methanone (CAS 1351587-01-3)
- 2-(2-(4-Bromo-2-fluorophenyl)-4-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-1H-imidazol-1-yl)ethanol (CAS 1282516-77-1)
- Rtitrexed Impurity 27 (CAS CATO-C4X-138627)
- Metronidazole Impurity 24 (CAS 3034-42-2)
- Metoprolol Impurity 20 (CAS 18995-35-2)
- N-cyclopropylbenzene-1,2-disulfonamide (CAS 105466-42-0)
- trans-2-[2-(3-Iodophenyl)-2-oxoethyl]-cyclopentane-1-carboxylic acid (CAS 733740-71-1)
- Ethyl 5-(chlorosulfonyl)-1-methyl-1h-pyrazole-4-carboxylate (CAS 88398-82-7)
- Ethyl 2-bromo-3-methylpyrazolo[1,5-a]pyrimidine-6-carboxylate (CAS 2090264-94-9)
- 1-(2,6-Dichlorophenyl)pentan-2-ol (CAS 1248931-89-6)
- 4-(3-Aminopropyl)-1,2,5-oxadiazole-3-carboxylic acid (CAS 884497-48-7)
- D-[Ser]8-Liraglutide (CAS CATO-C4X-199238)
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