Canagliflozin Impurity 76 CAS 2952941-15-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.2952941-15-8
Molecular FormulaC18H14FIS
Molecular Weight408.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Canagliflozin Impurity 76 CAS 2952941-15-8 chemical structure

Description

As a certified reference material (CRM), Canagliflozin Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Canagliflozin Impurity 76 (CAS 2952941-15-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H14FIS and a molecular weight of 408.27 g/mol.

Canagliflozin Impurity 76 (C18H14FIS) contains sulfur-containing functionality, fluorine/iodine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC18H14FIS
Molecular Weight408.27 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2004
Halogen ContentF/I-containing
Sulfur Atoms1

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