Empagliflozin Impurity 132 CAS 2452301-23-2
| CAS No. | 2452301-23-2 |
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Empagliflozin Impurity 132 (CAS 2452301-23-2) is a certified pharmaceutical impurity reference standard with the molecular formula C13H7ClFIO and a molecular weight of 360.55 g/mol.
The molecular framework of Empagliflozin Impurity 132 (C13H7ClFIO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Empagliflozin Impurity 132 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | F/Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 104 (CAS 76049-49-5)
- Empagliflozin impurity 247 (CAS CATO-C4X-1065247)
- Empagliflozin impurity 248 (CAS 143128-40-9)
- Empagliflozin impurity 252 (CAS CATO-C4X-1065252)
- Empagliflozin impurity 22 (CAS CATO-C4X-1065322)
- Empagliflozin Impurity 45 (CAS CATO-C4X-106545)
- Empagliflozin Impurity 91 (CAS 915095-86-2)
- Empagliflozin Impurity 145 (CAS CATO-C4X-1065145)
Recommended Standards
- 4-Chloro-3-fluoro-4-iodobenzophenone (CAS 951890-71-4)
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- 3-Chloro-4-fluoro-3-iodobenzophenone (CAS 951890-19-0)
- Olopatadine Impurity C504 HBr (CAS 27710-82-3)
- Avibactam Impurity 23 (CAS 1416134-49-0)
- Tofacitinib Impurity 53 (CAS 479633-63-1)
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- (1-Cyclohexylvinyl)boronic acid (CAS 1202245-69-9)
- 2-(3,4-Dimethoxyphenyl)ethane-1-thiol (CAS 62978-83-0)
- 5-Fluoro-1-methyl-1h-indazole-3-carboxylic acid (CAS 886368-88-3)
- (4-(Benzo[d][1,3]dioxol-5-yl)butan-2-yl)hydrazine (CAS 858830-96-3)
- Colistin Sulfate (Mixture of A and B compound) (CAS 1264-72-8)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com