Empagliflozin Impurity 45 CAS CATO-C4X-106545
| CAS No. | CATO-C4X-106545 |
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Empagliflozin Impurity 45 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Empagliflozin Impurity 45 (CAS CATO-C4X-106545), a pharmacopoeial impurity reference standard (molecular formula C13H7ClFIO, MW 360.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Empagliflozin Impurity 45 (C13H7ClFIO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 360.55 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 104 (CAS 76049-49-5)
- Empagliflozin Impurity 132 (CAS 2452301-23-2)
- Empagliflozin impurity 247 (CAS CATO-C4X-1065247)
- Empagliflozin impurity 248 (CAS 143128-40-9)
- Empagliflozin impurity 252 (CAS CATO-C4X-1065252)
- Empagliflozin impurity 22 (CAS CATO-C4X-1065322)
- Empagliflozin Impurity 91 (CAS 915095-86-2)
- Empagliflozin Impurity 145 (CAS CATO-C4X-1065145)
Recommended Standards
- 2-Acetamido-6-iodopyridine-4-sulfonyl chloride (CAS 1393531-40-2)
- 4-Acetamido-6-iodopyridine-2-sulfonyl chloride (CAS 1393582-75-6)
- 6-Acetamido-4-iodopyridine-2-sulfonyl chloride (CAS 1393583-26-0)
- (2S,3R,4R,5R)-5-(benzyloxymethyl)-3-[tert-butyl(dimethyl)silyl]oxy-tetrahydrofuran-2,4-diol (CAS 1583259-70-4)
- Palbociclib Impurity 115 (CAS 2399424-46-3)
- Brivaracetam Impurity 46 (CAS 2432911-31-2)
- Mebendazole impurity 3 (CAS CATO-C4X-27683)
- 4-Bromo-1-[(3-methylphenyl)methyl]-1h-pyrazol-3-amine (CAS 1004451-94-8)
- 2-[Bis(ethylsulfanyl)methyl]-4,5-dihydro-1,3-oxazole-4,5-dione (CAS 338975-28-3)
- Methyl 3-(5-Methyl-1,2,4-oxadiazol-3-yl)benzoate (CAS 1092566-65-8)
- 2-(1,6-dimethyl-1H-indol-3-yl)acetonitrile (CAS 202584-15-4)
- 1-Cyclopropoxy-4-ethyl-2-isopropylbenzene (CAS 1243453-22-6)
- 4-Chloro-1H-pyrrolo[2,3-c]pyridine-3-carbonitrile (CAS 2112620-28-5)
- Lixisenatide (CAS 320367-13-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com