Empagliflozin Impurity 104 CAS 76049-49-5
| CAS No. | 76049-49-5 |
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Empagliflozin Impurity 104.
Empagliflozin Impurity 104 (CAS 76049-49-5), molecular formula C13H7ClFIO and molecular weight 360.55 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Empagliflozin Impurity 104 (C13H7ClFIO) contains a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 360.55 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Empagliflozin Impurity 104 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H7ClFIO |
| Molecular Weight | 360.55 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | F/Cl/I-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 132 (CAS 2452301-23-2)
- Empagliflozin impurity 247 (CAS CATO-C4X-1065247)
- Empagliflozin impurity 248 (CAS 143128-40-9)
- Empagliflozin impurity 252 (CAS CATO-C4X-1065252)
- Empagliflozin impurity 22 (CAS CATO-C4X-1065322)
- Empagliflozin Impurity 45 (CAS CATO-C4X-106545)
- Empagliflozin Impurity 91 (CAS 915095-86-2)
- Empagliflozin Impurity 145 (CAS CATO-C4X-1065145)
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