Clotrimazole Impurity 17 CAS 717109-42-7
| CAS No. | 717109-42-7 |
| Molecular Formula | C20H17ClO |
| Molecular Weight | 308.80 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H17ClO, Clotrimazole Impurity 17 contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 308.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Clotrimazole Impurity 17 (CAS 717109-42-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H17ClO and a molecular weight of 308.80 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H17ClO |
| Molecular Weight | 308.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
Related Clotrimazole Standards
- Clotrimazole Impurity 8 (CAS CATO-C4X-15698)
- Clotrimazole EP Impurity F (CAS 15469-97-3)
- Clotrimazole Impurity 20 (CAS 27023-37-6)
- Clotrimazole Impurity 22 (CAS 59154-29-9)
- Clotrimazole EP Impurity C (CAS 42074-68-0)
- Clotrimazole Impurity 18 (CAS 717109-43-8)
- Clotrimazole EP Impurity A (CAS 66774-02-5)
- Clotrimazole Impurity 16 (CAS 6922-89-0)
Recommended Standards
- Dehydro desloratadine (CAS 117811-20-8)
- 4-Methoxytrityl chloride (CAS 14470-28-1)
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- 898780-40-0 1-(4-Chloro-2-fluorophenyl)-3-[2-(methylsulfanyl)phenyl]propan-1-one DTXSID00644342 (CAS 898780-40-0)
- Vilanterol Impurity 80 (CAS 2514963-34-7)
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- Liraglutide(8-31)TFA Salt (CAS CATO-C4X-19922)
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