Clotrimazole Impurity 25 CAS 3509-85-1
| CAS No. | 3509-85-1 |
| Molecular Formula | C13H9Cl3 |
| Molecular Weight | 271.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Clotrimazole Impurity 25.
Clotrimazole Impurity 25 (CAS 3509-85-1) is a certified pharmaceutical impurity reference standard with the molecular formula C13H9Cl3 and a molecular weight of 271.57 g/mol.
The molecular framework of Clotrimazole Impurity 25 (C13H9Cl3) is characterized by chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Clotrimazole Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9Cl3 |
| Molecular Weight | 271.57 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Clotrimazole Standards
- Clotrimazole Impurity 27 (CAS 56153-60-7)
- Clotrimazole Impurity 1 (CAS 968-39-8)
- Clotrimazole EP Impurity A (CAS 66774-02-5)
- Clotrimazole Impurity 16 (CAS 6922-89-0)
- Clotrimazole Impurity 21 (CAS 29647-82-3)
- Clotrimazole Impurity 17 (CAS 717109-42-7)
- Clotrimazole Impurity 8 (CAS CATO-C4X-15698)
- Clotrimazole EP Impurity F (CAS 15469-97-3)
Recommended Standards
- 8-Chloro-3-(difluoromethyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 478248-92-9)
- Pentadecanoic-d29 Acid (CAS 130348-95-7)
- 4,4-(Chloromethylene)bis(chlorobenzene) (CAS 782-08-1)
- 2,2,2-Trifluoroethyl (2-chloro-4-fluorophenyl)carbamate (CAS 1087797-94-1)
- Atogepant Impurity 83 (CAS CATO-C4X-328583)
- Imipenem Impurity 117 (CAS CATO-C4X-1662117)
- Alanyl Glutamine Impurity 31 (CAS 656221-79-3)
- 2-(2-aminoethyl)-6-bromophenol hydrobromide (CAS 1795187-83-5)
- (R)-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-ol (CAS 1932107-75-9)
- 3,5-Dimethyl-1-phenyl-1h-pyrazol-4-ol (CAS 16209-01-1)
- 1-(4-(Benzyloxy)phenyl)-2-((4-(benzyloxy)phenyl)amino)propan-1-one (CAS 1048697-94-4)
- (S)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(o-tolyl)butanoic acid (CAS 270062-91-4)
- 2-chloro-3-[2-chloro-4-(trifluoromethyl)phenyl]-N-(4-methoxyphenyl)propanamide (CAS 680215-65-0)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com