Trazodone Impurity 39 HCl CAS 333988-45-7
| CAS No. | 333988-45-7 |
| Molecular Formula | C9H11Cl2N |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trazodone Impurity 39 HCl is closely related to a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Trazodone Impurity 39 HCl (CAS 333988-45-7), a pharmacopoeial impurity reference standard (molecular formula C9H11Cl2NHCl, MW 240.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C9H11Cl2NHCl, Trazodone Impurity 39 HCl contains a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 240.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Trazodone Impurity 39 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11Cl2N HCl |
| Molecular Weight | 240.55 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trazodone Standards
- Trazodone Impurity N13 (CAS 101364-27-6)
- Trazodone D6 (CAS 1181578-48-2)
- Trazodone-d6 Hydrochloride (CAS 1181578-71-1)
- Trazodone Hydrochloride EP Impurity C (CAS 1263278-77-8)
- Trazodone Impurity 4 (CAS 1263278-79-0)
- Trazodone EP Impurity D HCl (CAS 1263278-80-3)
- Trazodone Hydrochloride EP Impurity J (CAS 1263358-12-8)
- Trazodone EP Impurity D (CAS 1263358-13-9)
Recommended Standards
- Cefazolin Impurity 74 (CAS CATO-C4X-157774)
- Regadenoson Impurity U18 (CAS 2096-10-8)
- Sitagliptin Impurity 52 (CAS 764667-64-3)
- (R)-2-(4-Fluorophenyl)-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)ethan-1-amine hydrochloride (CAS 1259300-11-2)
- Rel-2-(benzo[b]thiophen-4-yl)-N-methyl-N-((1R,2R)-2-(pyrrolidin-1-yl)cyclohexyl)acetamide (CAS 111728-01-9)
- Pazopanib Impurity 21 (CAS 6269-91-6)
- 4-Chloro-3-(2-dimethylaminoethoxy)phenylboronic acid (CAS 1256355-02-8)
- 1-(Difluoromethyl)-3-methoxynaphthalene (CAS 1261621-00-4)
- 2-Phenyloxetane-2-carbonitrile (CAS 38586-15-1)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com