Desloratadine Impurity 35 CAS 38092-88-5
| CAS No. | 38092-88-5 |
| Molecular Formula | C20H21ClN2 |
| Molecular Weight | 324.85 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Desloratadine Impurity 35 (C20H21ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 324.85 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Desloratadine Impurity 35 (CAS 38092-88-5) is a certified pharmaceutical impurity reference standard with the molecular formula C20H21ClN2 and a molecular weight of 324.85 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Desloratadine Impurity 35 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21ClN2 |
| Molecular Weight | 324.85 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Desloratadine Standards
- Desloratadine Impurity 30 (CAS 183198-48-3)
- Desloratadine Impurity 33 (CAS 38092-90-9)
- Desloratadine Impurity 48 (CAS 119770-61-5)
- Desloratadine Impurity 24 (CAS CATO-C4X-143024)
- Desloratadine Impurity 25 (CAS CATO-C4X-143025)
- Desloratadine Impurity 16 (CAS 1346604-23-6)
- Desloratadine Impurity 17 (CAS 169253-26-3)
- Desloratadine Impurity 22 (CAS 119410-05-8)
Recommended Standards
- N-(6-tert-Butyl-3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-2-chloropropanamide (CAS 1365963-84-3)
- Loratadine EP Impurity G (CAS 38092-89-6)
- 2-Chloro-N-[3-cyano-6-(1,1-dimethylpropyl)-4,5,6,7-tetrahydro-1-benzothien-2-yl]acetamide 4799AE 519016-57-0 C16H21ClN2OS (CAS 519016-57-0)
- Roxatidine Impurity 30 (CAS CATO-C4X-121330)
- Levosimendan impurity 75 (CAS CATO-C4X-130875)
- Palbociclib Impurity 88 (CAS 868591-58-6)
- Thioctic acid Impurity 34 (CAS CATO-C4X-152634)
- Bendamustine Impurity 37 (CAS CATO-C4X-127137)
- 4-(2-Chloroacetyl)-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 68321-41-5)
- tert-Butyl (1-(2-amino-1-(4-(trifluoromethyl)phenyl)ethyl)pyrrolidin-3-yl)carbamate (CAS 886365-38-4)
- Benzyl ((1s,3s)-3-aminocyclobutyl)carbamate (CAS 1212067-79-2)
- Benfotiamine (CAS 22457-89-2)
- 6-((Methylthio)methyl)-2-(pyridin-4-yl)pyrimidin-4(3H)-one (CAS 478031-31-1)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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