Fluconazole Impurity 6 CAS 51336-95-9
| CAS No. | 51336-95-9 |
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fluconazole Impurity 6 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Fluconazole Impurity 6 (CAS 51336-95-9), a pharmacopoeial impurity reference standard (molecular formula C8H5ClF2O, MW 190.57 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, Fluconazole Impurity 6 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 190.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF2O |
| Molecular Weight | 190.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F/Cl-containing |
Related Fluconazole Standards
- Fluconazole Impurity 11 (CAS 51336-94-8)
- Fluconazole Impurity 69 (CAS 98414-56-3)
- Fluconazole Impurity 7 (CAS 173837-65-5)
- Fluconazole Impurity 50 (CAS 58905-21-8)
- Fluconazole EP Impurity C (CAS 514222-44-7)
- Fluconazole Impurity 12 (CAS 188416-33-3)
- Fluconazole EP Impurity E (CAS 86404-63-9)
- Fluconazole Impurity 41 (CAS CATO-C4X-101941)
Recommended Standards
- ethyl 5-(chloromethyl)-1,2,4-oxadiazole-3-carboxylate (CAS 1009620-97-6)
- 2,3 - Difluoro - 4 - methylbenzoyl chloride 2,3-Difluoro-4-methyl-benzoyl chloride 2,3-difluoro-p-toluoyl chloride 261763-38-6 benzoyl chloride, 2,3-difluoro-4-methyl- (CAS 261763-38-6)
- 4-Chloro-5-methoxy-1-methyl-1H-pyrazole-3-carboxylic acid (CAS 1239759-59-1)
- Voriconazole Impurity N1 (CAS 929249-84-3)
- Loratadine Impurity 66 (CAS 65214-82-6)
- Clopidogrel Impurity 57 (CAS CATO-C4X-102957)
- Afoxolaner impurity 8 (CAS CATO-C4X-31378)
- Deglucohellebrin (CAS 20300-44-1)
- 3-(2-Chlorophenyl)pyrrolidineoxalate (CAS 1217062-15-1)
- 5-(3-Methoxyphenyl)-1H-pyrrole-2-carboxylic acid (CAS 1225551-48-3)
- (S)-2-((1-Benzylpiperidin-3-yl)(ethyl)amino)ethanol (CAS 1354015-25-0)
- N-[4-(4,5-Dichloro-1H-imidazol-1-yl)phenyl]-3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamide (CAS 1020252-49-6)
- (2R,3R,4S)-2-(6-Amino-9H-purin-9-yl)tetrahydrofuran-3,4-diol (CAS 14266-03-6)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com