Escitalopram EP Impurity H HCl CAS 62498-71-9
| CAS No. | 62498-71-9 |
| Molecular Formula | C20H21FN2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Escitalopram EP Impurity H HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Escitalopram EP Impurity H HCl (CAS 62498-71-9, C20H21FN2O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H21FN2O2HCl, Escitalopram EP Impurity H HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 376.86 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H21FN2O2 HCl |
| Molecular Weight | 376.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Escitalopram Standards
- Escitalopram Impurity 2 (CAS 103146-25-4)
- Escitalopram EP Impurity L Oxalate (CAS 1093072-86-6)
- Escitalopram Impurity 60 (CAS 1219803-58-3)
- Escitalopram USP Related Compound A (CAS 128173-53-5)
- Escitalopram EP Impurity K (CAS 128196-02-1)
- EsCitalopram EP Impurity I (CAS 1370643-22-3)
- Escitalopram EP Impurity M (CAS 1881237-26-8)
- Escitalopram EP Impurity F (CAS 2102609-59-4)
Recommended Standards
- Haloperidol EP Impurity B (CAS 1391052-53-1)
- CAS CATO-C4X-32402 (CAS CATO-C4X-32402)
- Levofloxacin Impurity 95 Sulfate (CAS CATO-C4X-137195)
- Cefdinir CP Impurity H Sodium Salt (CAS CATO-C4X-121078)
- Methyl 6-Quinoxalinecarboxylate (CAS 23088-23-5)
- Vonoprazan Impurity 251 (CAS CATO-C4X-1020251)
- 2-Chloro-4-morpholinoquinazoline (CAS 39213-05-3)
- 3-Bromo-6-fluoro-2-hydroxybenzonitrile (CAS 1521983-70-9)
- N-(1-Cyanocyclopentyl)-2-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetamide (CAS 851966-13-7)
- Neuropeptide K, porcine (CAS 106441-70-7)
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