Etoposide EP Impurity E CAS 6559-91-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.6559-91-7
Molecular FormulaC21H20O8
Molecular Weight400.38 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Etoposide EP Impurity E CAS 6559-91-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 400.38 g/mol gives Etoposide EP Impurity E distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Etoposide EP Impurity E (CAS 6559-91-7) is a certified pharmaceutical impurity reference standard with the molecular formula C21H20O8 and a molecular weight of 400.38 g/mol.

Based on its molecular formula C21H20O8, Etoposide EP Impurity E contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 400.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H20O8
Molecular Weight400.38 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at room temperature, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958

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