Verapamil EP Impurity J CAS 67018-85-3
| CAS No. | 67018-85-3 |
| Molecular Formula | C26H36N2O4 |
| Molecular Weight | 440.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Verapamil EP Impurity J.
Verapamil EP Impurity J (CAS 67018-85-3) is a certified pharmaceutical impurity reference standard with the molecular formula C26H36N2O4 and a molecular weight of 440.58 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Verapamil EP Impurity J is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Verapamil EP Impurity J under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H36N2O4 |
| Molecular Weight | 440.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1976 |
| Nitrogen Atoms | 2 |
Related Verapamil Standards
- (S)-(-)-Verapamil HCl (CAS 36622-29-4)
- Verapamil EP Impurity I (CAS 2893-91-6)
- Verapamil Impurity 36 (CAS 77326-93-3)
- Verapamil Impurity 37 (CAS 67018-80-8)
- Verapamil Impurity 38 (CAS 114847-42-6)
- Verapamil Impurity 39 (CAS 31910-93-7)
- Verapamil Impurity 44 (CAS CATO-C4X-177844)
- Verapamil EP Impurity H (CAS 67018-83-1)
Recommended Standards
- N,N'-Diphenyl-N,N'-di(m-tolyl)-1,4-phenylenediamine (CAS 80223-29-6)
- N-(2-Cyano-3-methylbutan-2-yl)-2-((5,6-dimethyl-4-oxo-3-phenyl-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 761420-54-6)
- AEE 788 (CAS 497839-62-0)
- 4-[(3-Methoxyphenyl)sulfanyl]-2-[(4-methylphenyl)methanesulfonyl]-5,6,7,8-tetrahydroquinazoline (CAS 478246-75-2)
- Baclofen Impurity 48 (CAS CATO-C4X-101248)
- Lemborexant Impurity 65 (CAS 3070371-35-3)
- Ceftriaxone EP Impurity D (CAS 80756-85-0)
- 2-Amino-5-(4-methylphenyl)-5-[(thiophen-2-yl)methyl]-4,5-dihydro-1H-imidazol-4-one (CAS 1354914-89-8)
- (E)-[(2,4-Dichlorophenyl)methoxy]({6-phenyl-2H,3H-imidazo[2,1-b][1,3]thiazol-5-yl}methylidene)amine (CAS 400080-08-2)
- 6-Benzyl-2-chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS 1233932-38-1)
- 2-(3-Fluorophenyl)butan-2-ol (CAS 76529-20-9)
- 3-Amino-N,N,3-trimethylbutanamide (CAS 854419-12-8)
- 1-(5-allyloxy-2-methyl-phenyl)hexahydropyrimidine-2,4-dione (CAS 2633635-26-2)
- Semaglutide impurity 94 (CAS CATO-C4X-222694)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com